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Literature summary for 2.4.2.64 extracted from
- tRNA-guanine transglycosylase and guanine-accepting transfer RNAs of Drosophila melanogaster (1980), Insect Biochem., 10, 183-188 .
No PubMed abstract available
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| guanine34 in tRNA + queuine | Drosophila melanogaster | - |
queuine34 in tRNA + guanine | - |
? |  |
| guanine34 in tRNA + queuine | Oryctolagus cuniculus | - |
queuine34 in tRNA + guanine | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Drosophila melanogaster | - |
- |
- |
| Oryctolagus cuniculus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| larva | the enzyme activity is present in third instar larvae and adult flies but is absent in late pupae | Drosophila melanogaster | - |
| pupa | the enzyme activity is present in third instar larvae and adult flies but is absent in late pupae | Drosophila melanogaster | - |
| reticulocyte | - |
Oryctolagus cuniculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| guanine34 in tRNA + queuine | - |
Drosophila melanogaster | queuine34 in tRNA + guanine | - |
? | |
| guanine34 in tRNA + queuine | - |
Oryctolagus cuniculus | queuine34 in tRNA + guanine | - |
? | |
| guanine34 in tRNA + queuine | the enzyme replaces a guanine in the anticodon of tRNAs for Asn, Asp, His, and Tyr. In the absence of queuine, this enzyme catalyzes an exchange between free guanine with guanine | Drosophila melanogaster | queuine34 in tRNA + guanine | - |
? | |
| guanine34 in tRNA + queuine | the enzyme replaces a guanine in the anticodon of tRNAs for Asn, Asp, His, and Tyr. In the absence of queuine, this enzyme catalyzes an exchange between free guanine with guanine | Oryctolagus cuniculus | queuine34 in tRNA + guanine | - |
? | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.4 | - |
- |
Drosophila melanogaster |
pH Range
| pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|
| 6.2 | 7.8 | pH 6.2: about 50% of maximal activity, pH 7.8: about 50% of maximal activity | Drosophila melanogaster |
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