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Literature summary for 2.4.2.4 extracted from

  • Li, W.; Gigante, A.; Perez-Perez, M.J.; Yue, H.; Hirano, M.; McIntyre, T.M.; Silverstein, R.L.
    Thymidine phosphorylase participates in platelet signaling and promotes thrombosis (2014), Circ. Res., 115, 997-1006.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.4.2.4

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
50000
-
 x * 50000, SDS-PAGE Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
thymidine + phosphate Mus musculus
-
 thymine + 2-deoxy-alpha-D-ribose 1-phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
blood platelet
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
thymidine + phosphate
-
 Mus musculus thymine + 2-deoxy-alpha-D-ribose 1-phosphate
-
 ?

Subunits

Subunits Comment Organism
? x * 50000, SDS-PAGE Mus musculus

Synonyms

Synonyms Comment Organism
TYMP
-
 Mus musculus

General Information

General Information Comment Organism
malfunction collagen-, collagen-related peptide-, adenosine diphosphate-and/or thrombin-induced platelet aggregation are significantly attenuated in enzyme deficient platelets. Tymp deficiency also significantly decreases agonist-induced P-select in expression Mus musculus
physiological function the enzyme participates in platelet signaling and promotes thrombosis by platelet activation Mus musculus