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Literature summary for 2.4.2.4 extracted from

  • Brockenbrough, J.S.; Morihara, J.K.; Hawes, S.E.; Stern, J.E.; Rasey, J.S.; Wiens, L.W.; Feng, Q.; Vesselle, H.
    Thymidine kinase 1 and thymidine phosphorylase expression in non-small-cell lung carcinoma in relation to angiogenesis and proliferation (2009), J. Histochem. Cytochem., 57, 1087-1097.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Homo sapiens
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Source Tissue

Source Tissue Comment Organism Textmining
non-small cell lung cancer cell similar distribution of thymidine phosphorylase and thymidine kinase, EC 2.7.1.21, immunohistochemical analysis, overview Homo sapiens
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General Information

General Information Comment Organism
metabolism the enzyme is involved in the thymidine salvage pathway and competes with thymidine kinase, overview. Thymidine plays a central role in both proliferation and angiogensis, overview Homo sapiens