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BRENDA support

Literature summary for 2.4.2.4 extracted from

  • Saif, M.W.; Black, G.; Roy, S.; Bell, D.; Russo, S.; Eloubeidi, M.A.; Steg, A.; Johnson, M.R.; Zelterman, D.; Diasio, R.B.
    Phase II study of capecitabine with concomitant radiotherapy for patients with locally advanced pancreatic cancer: up-regulation of thymidine phosphorylase (2007), Cancer J., 13, 247-256.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
interferon alpha2b induces thymidine phosphorylase mRNA and protein expression in a dose-dependent manner Homo sapiens
additional information 50.4 Gy radiation in combination with capecitabine leads to elevated thymidine phosphorylase activity Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
pancreatic cancer cell
-
Homo sapiens
-
RCC 786-O cell
-
Homo sapiens
-