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Literature summary for 2.4.2.4 extracted from

  • Kubilus, J.; Lee, L.D.; Baden, H.P.
    Purification of thymidine phosphorylase from human amniochorion (1978), Biochim. Biophys. Acta, 527, 221-228.
    View publication on PubMed
Search for more literature for 2.4.2.4

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
58000
-
 2 * 58000, SDS-PAGE, enzyme is capable of being converted to a less active form larger in MW and possibly trimeric or tetrameric in structure Homo sapiens
120000
-
 gel filtration Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
amniochorion
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
5.3
-
-
 Homo sapiens
320
-
-
 Homo sapiens

Storage Stability

Storage Stability Organism
4°C, storage results in a decrease of the 120 kDA component, an increase of the high molecular weight component, and a loss of activity Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
deoxythymidine + phosphate
-
 Homo sapiens thymine + 2-deoxy-D-ribose 1-phosphate
-
 ?
deoxyuridine + phosphate
-
 Homo sapiens uracil + 2-deoxy-D-ribose 1-phosphate
-
 ?
additional information no substrate: deoxycytidine Homo sapiens ?
-
 ?
thymidine + phosphate
-
 Homo sapiens thymine + 2-deoxy-D-ribose 1-phosphate
-
 ?

Subunits

Subunits Comment Organism
dimer 2 * 58000, SDS-PAGE, enzyme is capable of being converted to a less active form larger in MW and possibly trimeric or tetrameric in structure Homo sapiens