Application | Comment | Organism |
---|---|---|
medicine | the enzyme is a biomarker for myofibroblast differentiation and fibrotic development | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
dermal fibroblast | - |
Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
XT-I | - |
Homo sapiens |
xylosyltransferase-I | - |
Homo sapiens |
XYLT1 | - |
Homo sapiens |
Organism | Comment | Expression |
---|---|---|
Homo sapiens | isoform XYLT1 expression is inhibited by transforming growth factor-beta receptor I inhibitor SB431542 | down |
Homo sapiens | treatment of normal human dermal fibroblasts with transforming growth factor-beta1 is followed by increased relative isoform XYLT1 mRNA expression. Moreover, enzyme activity increases time-dependently in response to progressive myofibroblast transformation | up |
General Information | Comment | Organism |
---|---|---|
metabolism | the enzyme catalyzes the initial step of glycosaminoglycan biosynthesis | Homo sapiens |