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Literature summary for 2.4.2.31 extracted from

  • Yang, X.; Li, M.; Tang, Y.; Wang, Y.; Threadgill, M.; Han, J.; Han, X.; Chen, L.; Chen, H.; Hu, W.; Lin, X.
    ART1 induces aberrant methylation of uPA promoter A preliminary study (2016), Int. J. Clin. Exp. Pathol., 9, 4269-4282 .
No PubMed abstract available
Search for more literature for 2.4.2.31

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
NAD+ + protein L-arginine Mus musculus
-
 nicotinamide + Nomega-(ADP-D-ribosyl)-protein-L-arginine
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
Ni-NTA column chromatography Mus musculus

Source Tissue

Source Tissue Comment Organism Textmining
colorectal cancer cell
-
 Mus musculus
-
CT-26 cell
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
NAD+ + protein L-arginine
-
 Mus musculus nicotinamide + Nomega-(ADP-D-ribosyl)-protein-L-arginine
-
 ?

Subunits

Subunits Comment Organism
? x * 40000, SDS-PAGE Mus musculus

Synonyms

Synonyms Comment Organism
arginine ADP-ribosyltransferase 1
-
 Mus musculus
ART1
-
 Mus musculus

General Information

General Information Comment Organism
malfunction enzyme silencing induces hypermethylation of the urokinase plasminogen activator gene Mus musculus
physiological function enzyme over-expression causes hypomethylation of the urokinase plasminogen activator gene. The enzyme is related to the expression and activity of DNA methyltransferase 1 Mus musculus