Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
NAD+ + protein L-arginine | Mus musculus | - |
nicotinamide + Nomega-(ADP-D-ribosyl)-protein-L-arginine | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
Ni-NTA column chromatography | Mus musculus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
colorectal cancer cell | - |
Mus musculus | - |
CT-26 cell | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
NAD+ + protein L-arginine | - |
Mus musculus | nicotinamide + Nomega-(ADP-D-ribosyl)-protein-L-arginine | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 40000, SDS-PAGE | Mus musculus |
Synonyms | Comment | Organism |
---|---|---|
arginine ADP-ribosyltransferase 1 | - |
Mus musculus |
ART1 | - |
Mus musculus |
General Information | Comment | Organism |
---|---|---|
malfunction | enzyme silencing induces hypermethylation of the urokinase plasminogen activator gene | Mus musculus |
physiological function | enzyme over-expression causes hypomethylation of the urokinase plasminogen activator gene. The enzyme is related to the expression and activity of DNA methyltransferase 1 | Mus musculus |