Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
NAD+ + (ADP-D-ribosyl)n-NEMO protein | Homo sapiens | the enzyme prevents poly-ubiquitination of NEMO protein | nicotinamide + (ADP-D-ribosyl)n+1-NEMO protein + H+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q53GL7 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
HeLa cell | - |
Homo sapiens | - |
U2OS cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
NAD+ + (ADP-D-ribosyl)n-NEMO protein | the enzyme prevents poly-ubiquitination of NEMO protein | Homo sapiens | nicotinamide + (ADP-D-ribosyl)n+1-NEMO protein + H+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ARTD10 | formerly PARP10 | Homo sapiens |
mono-ADP-ribosyltransferase | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
metabolism | the enzyme inhibits the activation of NF-kappaB and downstream target genes in response to interleukin-1beta and tumour necrosis factor-alpha, dependent on catalytic activity and poly-ubiquitin binding | Homo sapiens |