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Literature summary for 2.4.2.30 extracted from
- Poly(ADP-ribose) polymerase 1 (PARP-1) regulates ribosomal biogenesis in Drosophila nucleoli (2012), PLoS Genet., 8, e1002442.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| nucleus | - |
Drosophila melanogaster | 5634 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Drosophila melanogaster | P35875 | - |
- |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| PARP1 | - |
Drosophila melanogaster |
General Information
| General Information | Comment | Organism |
|---|---|---|
| malfunction | disruption of PARP1 enzymatic activity causes nucleolar disintegration and aberrant localization of nucleolar-specific proteins. PARP1 mutants have increased accumulation of rRNA intermediates and a decrease in ribosome levels | Drosophila melanogaster |
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