Literature summary for 2.4.2.3 extracted from

Wang, J.; Xu, S.; Lv, W.; Shi, F.; Mei, S.; Shan, A.; Xu, J.; Yang, Y.
Uridine phosphorylase 1 is a novel immune-related target and predicts worse survival in brain glioma (2020), Cancer Med., 9, 5940-5947 .

Search for more literature for 2.4.2.3

Application

Application	Comment	Organism
diagnostics	UPP1 may serve as a negative prognosticator in glioma, analysis of the prognostic value of UPP1 for glioma, overview. UPP1 predicts shorter survival for glioma	Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
uracil + alpha-D-ribose 1-phosphate	Homo sapiens	-	uridine + phosphate	-	r

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	Q16831	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
glioblastoma cell	UPP1 is significantly upregulated in glioma, especially in glioblastoma	Homo sapiens	-
glioma cell	UPP1 is significantly upregulated in glioma, especially in glioblastoma	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
uracil + alpha-D-ribose 1-phosphate	-	Homo sapiens	uridine + phosphate	-	r

Synonyms

Synonyms	Comment	Organism
UPP1	-	Homo sapiens
uridine phosphorylase 1	-	Homo sapiens

Expression

Organism	Comment	Expression
Homo sapiens	UPP1 is significantly upregulated in glioma, especially in glioblastoma	up

General Information

General Information	Comment	Organism
physiological function	UPP1 interacts with immune checkpoint members in glioma	Homo sapiens

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Release 2023.1 (January 2023)