Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
HEK-293-EBNA cell | - |
Homo sapiens | - |
Hep-G2 cell | - |
Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
LARGE | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
malfunction | LARGE gene silencing in Hep-G2 and HEK-EBNA cells does not affect SERPINC1 mRNA levels but significantly reduces the secretion of antithrombin with moderate intracellular retention | Homo sapiens |
physiological function | LARGE is a modifier of plasma antithrombin | Homo sapiens |