Literature summary for 2.4.2.19 extracted from

Youn, H.S.; Kim, M.K.; Kang, G.B.; Kim, T.G.; Lee, J.G.; An, J.Y.; Park, K.R.; Lee, Y.; Kang, J.Y.; Song, H.E.; Park, I.; Cho, C.; Fukuoka, S.; Eom, S.H.
Crystal structure of Sus scrofa quinolinate phosphoribosyltransferase in complex with nicotinate mononucleotide (2013), PLoS ONE, 8, e62027.

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Crystallization (Commentary)

Crystallization (Comment)	Organism
in complex with nicotinate mononucleotide, hanging drop vapor diffusion method, using 100 mM Tris-HCl, pH 8.0, 16-24% (w/v) PEG 8000, 150-200 mM ammonium acetate	Sus scrofa

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
33000	-	6 * 33000, X-ray crystallography	Sus scrofa

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
beta-nicotinate D-ribonucleotide + diphosphate + CO2	Sus scrofa	-	pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate	-	?

Organism

Organism	UniProt	Comment	Textmining
Sus scrofa	M1KCW7	-	-

Purification (Commentary)

Purification (Comment)	Organism
ammonium sulfate precipitation and DEAE-Sephadex A-50 gel filtration	Sus scrofa

Source Tissue

Source Tissue	Comment	Organism	Textmining
kidney	-	Sus scrofa	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
beta-nicotinate D-ribonucleotide + diphosphate + CO2	-	Sus scrofa	pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate	-	?

Subunits

Subunits	Comment	Organism
hexamer	6 * 33000, X-ray crystallography	Sus scrofa

Synonyms

Synonyms	Comment	Organism
QAPRTase	-	Sus scrofa
quinolinate phosphoribosyltransferase	-	Sus scrofa

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Release 2023.1 (January 2023)