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Literature summary for 2.4.2.19 extracted from

  • Sinclair, S.J.; Murphy, K.J.; Birch, C.D.; Hamill, J.D.
    Molecular characterization of quinolinate phosphoribosyltransferase (QPRTase) in Nicotiana (2000), Plant Mol. Biol., 44, 603-617.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Nicotiana rustica
expression in Escherichia coli Nicotiana tabacum

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Nicotiana rustica key enzyme in NAD+ biosynthesis, also plays an important role in ensuring nicotinic acid available for the synthesis of defensive pyridine alkaloids ?
-
?
additional information Nicotiana tabacum key enzyme in NAD+ biosynthesis, also plays an important role in ensuring nicotinic acid available for the synthesis of defensive pyridine alkaloids ?
-
?
additional information Nicotiana sylvestris key enzyme in NAD+ biosynthesis, also plays an important role in ensuring nicotinic acid available for the synthesis of defensive pyridine alkaloids ?
-
?

Organism

Organism UniProt Comment Textmining
Nicotiana rustica
-
-
-
Nicotiana sylvestris
-
-
-
Nicotiana tabacum
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
root
-
Nicotiana sylvestris
-
root transcript level increases markedly 12-24 h after damage to aerial tissue Nicotiana rustica
-
root transcript level increases markedly 12-24 h after damage to aerial tissue Nicotiana tabacum
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information key enzyme in NAD+ biosynthesis, also plays an important role in ensuring nicotinic acid available for the synthesis of defensive pyridine alkaloids Nicotiana rustica ?
-
?
additional information key enzyme in NAD+ biosynthesis, also plays an important role in ensuring nicotinic acid available for the synthesis of defensive pyridine alkaloids Nicotiana tabacum ?
-
?
additional information key enzyme in NAD+ biosynthesis, also plays an important role in ensuring nicotinic acid available for the synthesis of defensive pyridine alkaloids Nicotiana sylvestris ?
-
?
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate
-
Nicotiana rustica nicotinate D-ribonucleotide + diphosphate + CO2
-
?
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate
-
Nicotiana tabacum nicotinate D-ribonucleotide + diphosphate + CO2
-
?
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate
-
Nicotiana sylvestris nicotinate D-ribonucleotide + diphosphate + CO2
-
?