Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
nicotinamide D-ribonucleotide + diphosphate | Mus musculus | - |
nicotinamide + 5-phospho-alpha-D-ribose 1-diphosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | Q99KQ4 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
nicotinamide D-ribonucleotide + diphosphate | - |
Mus musculus | nicotinamide + 5-phospho-alpha-D-ribose 1-diphosphate | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 56000, SDS-PAGE | Mus musculus |
Synonyms | Comment | Organism |
---|---|---|
Nampt | - |
Mus musculus |
General Information | Comment | Organism |
---|---|---|
malfunction | homozygous enzyme knockout results in lethality at an early stage of mouse embryonic development and death within 5-10 days in adult mice accompanied by a 25.24% body weight loss | Mus musculus |
physiological function | the enzyme is an essential gene for adult mouse survival. The enzyme is involved in key basic cellular functions such as transcription, translation, cell signaling, and fundamental metabolism | Mus musculus |