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Literature summary for 2.4.2.10 extracted from
- Orotate phosphoribosyltransferase expression level in tumors is a potential determinant of the efficacy of 5-fluorouracil (2007), Biochem. Biophys. Res. Commun., 363, 216-222.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | the OPRT mRNA level is positively correlated with the 5-fluorouracil efficacy in antitumor therapy | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| additional information | NCI-60 cell panel | Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| orotate + 5-phospho-alpha-D-ribose 1-diphosphate | - |
Homo sapiens | orotidine 5'-phosphate + diphosphate | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| OPRT | - |
Homo sapiens |
| orotidine 5'-monophosphate pyrophosphorylase | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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