Literature summary for 2.4.2.10 extracted from

Santiago, M.F.; West, T.P.
Control of pyrimidine formation in Pseudomonas putida ATCC 17536 (2002), Can. J. Microbiol., 48, 1076-1081.

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Inhibitors

Inhibitors	Comment	Organism	Structure
Orotic acid	when grown on glucose as carbon source, supplementation with orotic acid significantly decreases orotate phosphoribosyltransferase and orotidine 5'-monophoshate decarboxylase activities. In a strain deficient for dihydroorotase activity, orotic acid induces both phosphoribosyltransferase and orotidine 5'-monophoshate decarboxylase activites	Pseudomonas putida

Organism

Organism	UniProt	Comment	Textmining
Pseudomonas putida	-	strain ATCC 17536. When grown on glucose as carbon source, supplementation with orotic acid significantly decreases orotate phosphoribosyltransferase and orotidine 5'-monophoshate decarboxylase activities. In a strain deficient for dihydroorotase activity, orotic acid induces both phosphoribosyltransferase and orotidine 5'-monophoshate decarboxylase activites	-

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Release 2023.1 (January 2023)