Literature summary for 2.4.1.92 extracted from

Wang, H.R.; Hsieh, C.Y.; Twu, Y.C.; Yu, L.C.
Expression of the human Sda beta-1,4-N-acetylgalactosaminyltransferase II gene is dependent on the promoter methylation status (2008), Glycobiology, 18, 104-113.

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Activating Compound

Activating Compound	Comment	Organism	Structure
additional information	promoter DNA methylation plays a crucial role in the regulation of the Sda beta4GalNAcT-II gene and Sda antigen expression	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
colonic cancer cell	-	Homo sapiens	-
gastric cancer cell	-	Homo sapiens	-
gastric mucosa	-	Homo sapiens	-
KATO-III cell	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
UDP-N-acetyl-D-galactosamine + (N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide	-	Homo sapiens	UDP + N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide	-	?

Synonyms

Synonyms	Comment	Organism
beta-1,4-N-acetylgalactosyltransferase II	-	Homo sapiens
beta4GalNAcT-II	-	Homo sapiens
Sda beta-1,4-N-acetylgalactosaminyltransferase II	-	Homo sapiens

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Release 2023.1 (January 2023)