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Literature summary for 2.4.1.90 extracted from

  • Jiang, J.; Wagner, G.K.
    An acceptor analogue of beta-1,4-galactosyltransferase Substrate, inhibitor, or both? (2017), Carbohydr. Res., 450, 54-59 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.4.1.90

Activating Compound

Activating Compound Comment Organism Structure
bovine serum albumin in the presence of 12.5 mg/ml bovine serum albumin, turnover rates increase approximately 2fold and Km values increase by approximately 4fold, for both N-acetyl-D-glucosamine and 1-(2-naphthyl) 2-acetamido-2-deoxy-beta-D-glucopyranoside Bos taurus

Inhibitors

Inhibitors Comment Organism Structure
additional information not inhibited by 1-(2-naphthyl) 2-acetamido-2-deoxy-beta-D-glucopyranoside Bos taurus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.00008
-
 1-(2-naphthyl) 2-acetamido-2-deoxy-beta-D-glucopyranoside in the absence of bovine serum albumin, at pH 7.0 and 30°C Bos taurus
0.0003
-
 1-(2-naphthyl) 2-acetamido-2-deoxy-beta-D-glucopyranoside in the presence of 12.5 mg/ml bovine serum albumin, at pH 7.0 and 30°C Bos taurus
0.0004
-
 N-acetyl-D-glucosamine in the absence of bovine serum albumin, at pH 7.0 and 30°C Bos taurus
0.0015
-
 N-acetyl-D-glucosamine in the presence of 12.5 mg/ml bovine serum albumin, at pH 7.0 and 30°C Bos taurus

Metals/Ions

Metals/Ions Comment Organism Structure
Mn2+ 5 mM used in assay conditions Bos taurus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
UDP-alpha-D-galactose + N-acetyl-D-glucosamine Bos taurus
-
 UDP + N-acetyllactosamine
-
 ?

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
milk
-
 Bos taurus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UDP-alpha-D-galactose + 1-(2-naphthyl) 2-acetamido-2-deoxy-beta-D-glucopyranoside
-
 Bos taurus UDP + ?
-
 ?
UDP-alpha-D-galactose + N-acetyl-D-glucosamine
-
 Bos taurus UDP + N-acetyllactosamine
-
 ?

Synonyms

Synonyms Comment Organism
beta-1,4-galactosyltransferase
-
 Bos taurus
beta-1,4-GalT
-
 Bos taurus