Activating Compound | Comment | Organism | Structure |
---|---|---|---|
lysophosphatidylcholine | activates | Mus musculus | |
phosphatidylcholine | activates | Mus musculus | |
sphingomyelin | activates | Mus musculus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
GDP | 0.1 mM, 75% inhibition | Mus musculus | |
GMP | 1 mM, 75% inhibition | Mus musculus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00133 | - |
GDPmannose | - |
Mus musculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | outer membrane | Mus musculus | 5739 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | stimulation by addition of divalent cations, maximal stimulation at 5 mM | Mus musculus | |
Mn2+ | stimulation by divalent cation, Mn2+ is less effective than Mg2+ | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Mus musculus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Mus musculus | - |
Storage Stability | Organism |
---|---|
4°C, enzyme is relatively stable when stored overnight in phosphate buffer and retains full activity when stored within liposomes | Mus musculus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
GDPmannose + dolichyl phosphate | - |
Mus musculus | GDP + dolichyl D-mannosyl phosphate | - |
? |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
6.1 | - |
Mes buffer or sodium/potassium phosphate buffer | Mus musculus |