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Literature summary for 2.4.1.69 extracted from

  • Karaivanova, V.; Mookerjea, S.; Hunt, D.; Nagpurkar, A.
    Characterization and purification of fucosyltransferases from the cytosol of rat colon (1996), Int. J. Biochem. Cell Biol., 28, 165-174.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
Cu2+
-
Rattus norvegicus
NEM 20 mM, 72% inhibition Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
Rattus norvegicus 5829
-
membrane bound to Rattus norvegicus 16020
-
soluble
-
Rattus norvegicus
-
-

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ soluble and membrane-bound enzyme are active in absence of added cations, but addition of 10 mM Mn2+, Mg2+ or Ca2+ stimulates Rattus norvegicus
Mg2+ soluble and membrane-bound enzyme are active in absence of added cations, but addition of 10 mM Mn2+, Mg2+ or Ca2+ stimulates Rattus norvegicus
Mn2+ soluble and membrane-bound enzyme are active in absence of added cations, but addition of 10 mM Mn2+, Mg2+ or Ca2+ stimulates Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
colon
-
Rattus norvegicus
-
jejunum
-
Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
GDP-L-fucose + beta-D-galactosyl-R
-
Rattus norvegicus GDP + alpha-L-fucosyl-1,2-beta-D-galactosyl-R
-
?
GDP-L-fucose + phenyl-beta-D-galactoside
-
Rattus norvegicus GDP + phenyl 2-O-(alpha-L-fucopyranosyl)-beta-D-galactopyranoside
-
?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
5.8
-
soluble enzyme Rattus norvegicus
6
-
membrane-bound enzyme Rattus norvegicus