Inhibitors | Comment | Organism | Structure |
---|---|---|---|
EDTA | - |
Cavia porcellus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | membrane-bound | Cavia porcellus | 16020 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | activates, Mn2+ is most efficient, followed by Co2+, Mg2+ and Ca2+ | Cavia porcellus | |
Co2+ | activates, Mn2+ is most efficient, followed by Co2+, Mg2+ and Ca2+ | Cavia porcellus | |
Mg2+ | activates, Mn2+ is most efficient, followed by Co2+, Mg2+ and Ca2+ | Cavia porcellus | |
Mn2+ | activates, Mn2+ is most efficient, followed by Co2+, Mg2+ and Ca2+ | Cavia porcellus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
UDP-glucose + 5-(D-galactosyloxy)-L-lysine-procollagen | Cavia porcellus | probably postribosomal, attachment of galactose and glucose to hydroxylysine in collagen could conceivably function as part of the control mechanism signaling completion of the molecule and initiating its release | UDP + 1,2-D-glucosyl-5-D-(galactosyloxy)-L-lysine-procollagen | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Cavia porcellus | - |
male embryonic | - |
Purification (Comment) | Organism |
---|---|
100fold | Cavia porcellus |
skin, partial, solubilized with Triton X-100 | Cavia porcellus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
cartilage | embryonic | Cavia porcellus | - |
cartilage | cartilaginous ends of limb bone rudiments | Cavia porcellus | - |
embryo | embryo cartilage | Cavia porcellus | - |
embryo | embryonic skin | Cavia porcellus | - |
skin | embryonic skin | Cavia porcellus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | not: porcine submaxillary glycoprotein, galactose, galactosamine, N-acetylgalactosamine | Cavia porcellus | ? | - |
? | |
UDP-glucose + 5-(D-galactosyloxy)-L-lysine-procollagen | highly specific | Cavia porcellus | UDP + 1,2-D-glucosyl-5-D-(galactosyloxy)-L-lysine-procollagen | - |
? | |
UDP-glucose + 5-(D-galactosyloxy)-L-lysine-procollagen | tendon collagen | Cavia porcellus | UDP + 1,2-D-glucosyl-5-D-(galactosyloxy)-L-lysine-procollagen | - |
? | |
UDP-glucose + 5-(D-galactosyloxy)-L-lysine-procollagen | citrate-soluble guinea pig skin collagen | Cavia porcellus | UDP + 1,2-D-glucosyl-5-D-(galactosyloxy)-L-lysine-procollagen | - |
? | |
UDP-glucose + 5-(D-galactosyloxy)-L-lysine-procollagen | calf skin collagen | Cavia porcellus | UDP + 1,2-D-glucosyl-5-D-(galactosyloxy)-L-lysine-procollagen | - |
? | |
UDP-glucose + 5-(D-galactosyloxy)-L-lysine-procollagen | non-functional substrates, such as alpha1-glycoprotein and fetuin can replace collagen to some extent | Cavia porcellus | UDP + 1,2-D-glucosyl-5-D-(galactosyloxy)-L-lysine-procollagen | - |
? | |
UDP-glucose + 5-(D-galactosyloxy)-L-lysine-procollagen | probably postribosomal, attachment of galactose and glucose to hydroxylysine in collagen could conceivably function as part of the control mechanism signaling completion of the molecule and initiating its release | Cavia porcellus | UDP + 1,2-D-glucosyl-5-D-(galactosyloxy)-L-lysine-procollagen | - |
? | |
UDP-glucose + asialo alpha 1-glycoprotein | non-functional substrates, such as alpha1-glycoprotein and fetuin can replace collagen to some extent, poor substrate | Cavia porcellus | ? | - |
? | |
UDP-glucose + fetuin minus sialic acid, galactose and N-acetylglucosamine | non-functional substrates, such as alpha1-glycoprotein minus sialic acid and fetuin can replace collagen to some extent, poor substrate, fetuin minus sialic acid and galactose is a better substrate than fetuin | Cavia porcellus | ? | - |
? |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Cavia porcellus |
37 | - |
skin enzyme, optimum | Cavia porcellus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
5.8 | - |
skin enzyme | Cavia porcellus |