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Literature summary for 2.4.1.65 extracted from

  • Lin, C.H.; Lin, C.W.; Khoo, K.H.
    Proteomic identification of specific glycosyltransferases functionally implicated for the biosynthesis of a targeted glyco-epitope (2008), Proteomics, 8, 475-483.
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining
Golgi membrane
-
Homo sapiens 139
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Organism

Organism UniProt Comment Textmining
Homo sapiens P21217 FucT3
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Homo sapiens P51993 FucT6
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Purification (Commentary)

Purification (Comment) Organism
native enzyme by preparation of microsome and Golgi membrane fractions, ultracentrifugation, and affinity chromatography Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
Colo-205 cell
-
Homo sapiens
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information FucT3 and FucT5 possess alpha1,4FucT activity to fucosylate type 1 chains, but FucT3, as well as FucT6, account also for alpha3-fucosylation of type 2 chain in Colo205. FucT3 alone is responsible for synthesizing Lea and (sialyl) Lewis a, (sialyl)Galb1-(Fucalpha1-4)3GlcNAcbeta-(s)Lea in Colo205 Homo sapiens ?
-
?
additional information FucT3 and FucT5 possess alpha1,4FucT activity to fucosylate type 1 chains, but FucT3, as well as FucT6, account also for alpha3-fucosylation of type 2 chain in Colo205. FucT3 alone is responsible for synthesizing Lea and (sialyl) Lewis a, (sialyl)Galbeta1-(Fucalpha1-4)3GlcNAcbeta-(s)Lea in Colo205 Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
alpha3/4FucT
-
Homo sapiens