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Literature summary for 2.4.1.62 extracted from
- Purification, properties, and immunological characterization of GalT-3 (UDP-galactose: GM2 ganglioside, beta1-3 galactosyltransferase) from embryonic chicken brain (1995), Glycoconjugate J., 12, 838-847.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| ovine-asialo-agalacto submaxillary mucin | - |
Gallus gallus |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.022 | - |
UDP-galactose | - |
Gallus gallus |  |
| 0.033 | - |
N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-1,4-beta-D-glucosyl-N-acylsphingosine | - |
Gallus gallus | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| Golgi membrane | - |
Gallus gallus | 139 | - |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mn2+ | required, Km-value: 14.4 mM | Gallus gallus | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 62000 | - |
SDS-PAGE | Gallus gallus |
| 65000 | - |
native PAGE, sucrose-density gradient centrifugation | Gallus gallus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| UDP-galactose + asialo-GM2 | Gallus gallus | i.e. Gg3 | UDP + asialo-GM1 | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Gallus gallus | - |
embryonic | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Gallus gallus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | - |
Gallus gallus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 0.463 | - |
purified enzyme | Gallus gallus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | N-acetylgalactosamine and p-nitrophenyl-N-acetylgalactosamine are no substrates | Gallus gallus | ? | - |
? | |
| UDP-galactose + asialo-GM2 | i.e. Gg3 | Gallus gallus | UDP + asialo-GM1 | - |
? | |
| UDP-galactose + N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-1,4-beta-D-glucosyl-N-acylsphingosine | donor and acceptor specificity, overview | Gallus gallus | UDP + D-galactosyl-1,3-beta-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosyl-N-acylsphingosine | i.e. GM1 ganglioside or monosialoganglioside | ? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| monomer | 1 * 62000, form 1, SDS-PAGE | Gallus gallus |
| monomer | 1 * 65000, form 2, SDS-PAGE | Gallus gallus |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| GalT-3 | - |
Gallus gallus |
| UDP-galactose:GM2 ganglioside beta1-3 galactosyltransferase | - |
Gallus gallus |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
assay at | Gallus gallus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7 | - |
assay at | Gallus gallus |
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