Literature summary for 2.4.1.47 extracted from

Rzechonek, A.; Cygan, M.; Blasiak, P.; Muszczynska-Bernhard, B.; Bobek, V.; Lubicz, M.; Adamiak, J.
Expression of ceramide calactosyltransferase (UGT8) in primary and metastatic lung tissues of non-small-cell lung cancer (2016), Adv. Exp. Med. Biol., 952, 51-58 .

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Application

Application	Comment	Organism
medicine	study on UGT8 expression in tissue specimens of primary and corresponding metastatic lung tumors in 19 non-small cell lung carcinoma patients undergoing surgery. The majority of both lung primary and metastatic tumor tissues are positive in UGT8 signals. The cytoplasmic expression of UGT8 is found in 68.4% of cases of primary tumors and 82.2% of metastases, with a positive correlation between the UGT8 expression in both tumor tissues. The normal tissue adjacent to tumors shows no positive UGT8 staining. There is no appreciable difference in UGT8 expression depending on the clinical stage of non-small cell lung carcinoma or lymph node involvement found nor is there any association between UGT8 expression in tumor tissues and patients' survival time. UGT8, although enhanced in non-small cell lung carcinoma tissues, does not meet the criteria of a lung tumor marker	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	Q16880	-	-

Synonyms

Synonyms	Comment	Organism
UGT8	-	Homo sapiens

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Release 2023.1 (January 2023)