Literature summary for 2.4.1.41 extracted from

Brockhausen, I.; Dowler, T.; Paulsen, H.
Site directed processing: role of amino acid sequences and glycosylation of acceptor glycopeptides in the assembly of extended mucin type O-glycan core 2 (2009), Biochim. Biophys. Acta, 1790, 1244-1257.

Search for more literature for 2.4.1.41

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
0.24	-	AQPTPPP	-	Bos taurus
0.25	-	N-acetyl-4-benzoyl-L-Phe-L-Pro-L-Tyr-L-Pro-L-Pro-L-Pro-NH2	-	Bos taurus
0.3	-	N-acetyl-4-benzoyl-L-Phe-L-Pro-L-Tyr-L-Pro-L-Pro-L-Pro-NH2	-	Bos taurus
3.7	-	Ac-TPPA	-	Bos taurus

Organism

Organism	UniProt	Comment	Textmining
Bos taurus	-	-	-
Homo sapiens	Q10472	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
A-549 cell	-	Homo sapiens	-
lung epithelial cell	-	Bos taurus	-
lung epithelial cell	-	Homo sapiens	-
NCI-H292 cell	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
UDP-GalNAc + Ac-TPPA	pH 7.5, 37°C	Bos taurus	UDP + Ac-(GalNAcalpha1-)TPPA	-	?
UDP-GalNAc + AQPTPPP	pH 7.5, 37°C, 0.2 mM, 100% activity	Bos taurus	UDP + AQP-(GalNAcalpha1-)TPPP	-	?
UDP-GalNAc + N-acetyl-4-benzoyl-L-Phe-L-Pro-L-Tyr-L-Pro-L-Pro-L-Pro-NH2	pH 7.5, 37°C	Bos taurus	UDP + N-acetyl-4-benzoyl-L-Phe-L-Pro-L-(GalNAcalpha1-)Tyr-L-Pro-L-Pro-L-Pro-NH2	-	?
UDP-GalNAc + PTTTPITTTG	pH 7.5, 37°C, 0.2 mM, 26% activity relative to AQPTPPP	Bos taurus	UDP + P-(GalNAcalpha1-)TTTPITTTG + P-(GalNAcalpha1-)TTTPI-(GalNAcalpha1-)TTTG	-	?
UDP-GalNAc + TPTGTQTPTG	pH 7.5, 37°C, 0.2 mM, 8% activity relative to AQPTPPP	Bos taurus	UDP + TPTG-(GalNAcalpha1-)TQTPTG	-	?
UDP-GalNAc + TTTVTPTPTG	pH 7.5, 37°C, 0.2 mM, 109% activity relative to AQPTPPP	Bos taurus	UDP + TTTV-(GalNAcalpha1-)TPTPTG + T-(GalNAcalpha1-)TTV-(GalNAcalpha1-)TPTPTG + T-(GalNAcalpha1-)T-(GalNAcalpha1-)TV-(GalNAcalpha1-)TP-(GalNAcalpha1-)TPTG + T-(GalNAcalpha1-)TTV-(GalNAcalpha1-)TP-(GalNAcalpha1-)TP-(GalNAcalpha1-)TG + TT-(GalNAcalpha1-)TV-(GalNAcalpha1-)TPTPTG + ?	monoglycosylated product appears after 30 min, higher glycosylated products appear with increasing time of incubation	?
UDP-GalNAc + TVTPTPTPTG	pH 7.5, 37°C, 0.2 mM, 145% activity relative to AQPTPPP	Bos taurus	UDP + TVTP-(GalNAcalpha1-)TPTPTG	-	?

Synonyms

Synonyms	Comment	Organism
GalNAc-transferase	-	Bos taurus
GalNAc-transferase	-	Homo sapiens
GalNAc-transferase T1	-	Bos taurus
GalNAc-transferase T1	-	Homo sapiens
ppGalNAc-T	-	Bos taurus
ppGalNAc-T	-	Homo sapiens

Temperature Optimum [°C]

Temperature Optimum [°C]	Temperature Optimum Maximum [°C]	Comment	Organism
37	-	assay at	Bos taurus
37	-	assay at	Homo sapiens

pH Optimum

pH Optimum Minimum	pH Optimum Maximum	Comment	Organism
7.5	-	assay at	Bos taurus
7.5	-	assay at	Homo sapiens

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)