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Literature summary for 2.4.1.41 extracted from

  • Nakamura, N.; Toba, S.; Hirai, M.; Morishita, S.; Mikami, T.; Konishi, M.; Itoh, N.; Kurosaka, A.
    Cloning and expression of a brain-specific putative UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase gene (2005), Biol. Pharm. Bull., 28, 429-433.
    View publication on PubMed
Search for more literature for 2.4.1.41

Cloned(Commentary)

Cloned (Comment) Organism
-
 Rattus norvegicus
recombinant human pt-GalNAc-T, which is expressed in insect cells, does not glycosylate several peptides derived from mammalian mucins Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
UDP-N-acetyl-D-galactosamine + polypeptide Rattus norvegicus the enzyme is involved in the normal development of the brain through O-glycosylation of proteins in the neurons UDP + N-acetyl-D-galactosaminyl-polypeptide
-
 ?
UDP-N-acetyl-D-galactosamine + polypeptide Homo sapiens the enzyme is involved in the normal development of the brain through O-glycosylation of proteins in the neurons UDP + N-acetyl-D-galactosaminyl-polypeptide
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens Q9HCQ5
-
-
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Rattus norvegicus
-
brain high levels of expression in cerebellum, hippocampus, thalamus, and cerebral cortex. Expression is associated with neurons, but not with glial cells Homo sapiens
-
cerebellum
-
 Homo sapiens
-
cerebral cortex
-
 Homo sapiens
-
diencephalon
-
 Rattus norvegicus
-
ganglion dorsal root Rattus norvegicus
-
hippocampus
-
 Homo sapiens
-
nervous system
-
 Rattus norvegicus
-
neuron
-
 Homo sapiens
-
primordium cerebellar Rattus norvegicus
-
thalamus
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UDP-N-acetyl-D-galactosamine + polypeptide the enzyme is involved in the normal development of the brain through O-glycosylation of proteins in the neurons Rattus norvegicus UDP + N-acetyl-D-galactosaminyl-polypeptide
-
 ?
UDP-N-acetyl-D-galactosamine + polypeptide the enzyme is involved in the normal development of the brain through O-glycosylation of proteins in the neurons Homo sapiens UDP + N-acetyl-D-galactosaminyl-polypeptide
-
 ?

Synonyms

Synonyms Comment Organism
UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase
-
 Homo sapiens
UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 9
-
 Rattus norvegicus