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Literature summary for 2.4.1.41 extracted from

  • Wragg, S.; Hagen, F.K.; Tabak, L.A.
    Kinetic analysis of a recombinant UDP-N-acetyl-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (1995), J. Biol. Chem., 270, 16947-16954.
    View publication on PubMed
Search for more literature for 2.4.1.41

Cloned(Commentary)

Cloned (Comment) Organism
expression in COS7 cells as soluble His-tagged protein, secretion to the medium Bos taurus

Inhibitors

Inhibitors Comment Organism Structure
additional information
-
 Bos taurus
UDP competitive Bos taurus

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
recombinant soluble His-tagged enzyme from Cos-7 cells, purification from the medium Bos taurus

Reaction

Reaction Comment Organism Reaction ID
UDP-N-acetyl-alpha-D-galactosamine + [protein]-L-serine = UDP + [protein]-3-O-(N-acetyl-alpha-D-galactosaminyl)-L-serine mechanism Bos taurus
a

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UDP-N-acetyl-D-galactosamine + AcTPPP
-
 Bos taurus UDP + N-acetyl-D-galactosaminyl-AcTPPP
-
 ?
UDP-N-acetyl-D-galactosamine + PHMAQVTVGPGL
-
 Bos taurus UDP + N-acetyl-D-galactosaminyl-PHMAQVTVGPGL
-
 ?
UDP-N-acetyl-D-galactosamine + polypeptide
-
 Bos taurus UDP + N-acetyl-D-galactosaminyl-polypeptide
-
 ?
UDP-N-acetyl-D-galactosamine + PPDAATAAPLR i.e. EPO-T peptide Bos taurus UDP + N-acetyl-D-galactosaminyl-PPDAATAAPLR
-
 ?

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
additional information
-
 additional information
-
 Bos taurus