Application | Comment | Organism |
---|---|---|
medicine | construction of bivalent vaccines for preventing both Salmonella typhimurium and Salmonella newport infections by using the aspartate semialdehyde dehydrogenase-based balanced-lethal vector-host system. The constructed plasmid pCZ11 carrying a subset of the Salmonella newport O-antigen gene cluster including the wzx-wbaR-wbaL-wbaQ-wzy-wbaW-wbaZ genes is introduced into Salmonella typhimurium. Upon deletion of the crp gene for attenuation purposes, BALB/c mice are orally immunized with the strains. Compared with a mock immunization, immunization with the vaccine strains induces significant serum IgG responses against both Salmonella typhimurium and Salmonella newport lipopolysaccharide | Salmonella enterica subsp. enterica serovar Newport |
Organism | UniProt | Comment | Textmining |
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Salmonella enterica subsp. enterica serovar Newport | - |
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Synonyms | Comment | Organism |
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wbaQ | - |
Salmonella enterica subsp. enterica serovar Newport |