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Literature summary for 2.4.1.37 extracted from
- ABO blood group A transferase and its codon 69 substitution enzymes synthesize FORS1 antigen of FORS blood group system (2019), Sci. Rep., 9, 9717 .
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expression in COS-1 cell | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | P16442 | - |
- |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | the deletion of exon 3 or 4, but not of exon 2 or 5, of human GTA transcripts bestows moderate Forssman glycolipid synthase activity. Strong Forssman glycolipid synthase activity is attained, in addition to GTA and GTB activities, by cointroducing one of those deletions and the replacement of the LeuGlyGly tripeptide sequence at codons 266 to 268 by GlyGlyAla substitution, i.e. to the residues of Forssman glycolipid synthase | Homo sapiens |
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Release 2023.1 (January 2023)
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