Literature summary for 2.4.1.37 extracted from

Gagnon, S.M.L.; Legg, M.S.G.; Sindhuwinata, N.; Letts, J.A.; Johal, A.R.; Schuman, B.; Borisova, S.N.; Palcic, M.M.; Peters, T.; Evans, S.V.
High-resolution crystal structures and STD NMR mapping of human ABO(H) blood group glycosyltransferases in complex with trisaccharide reaction products suggest a molecular basis for product release (2017), Glycobiology, 27, 966-977 .

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Crystallization (Commentary)

Crystallization (Comment)	Organism
structures of isoforms GTA and GTB in complex with their respective trisaccharide products. A conflict exists between the transferred sugar monosaccharide and the beta-phosphate of the UDP donor. The mechanism of product release shows monosaccharide transfer to the H-antigen acceptor induces active site disorder and ejection of the UDP leaving group prior to trisaccharide egress	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P16442	-	-

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Release 2023.1 (January 2023)