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Literature summary for 2.4.1.37 extracted from

  • Turcot, A.L.; Blancher, A.; Le Moullac-Vaidye, B.; Despiau, S.; Rocher, J.; Roubinet, F.; Szpirer, C.; Le Pendu, J.
    Cloning of a rat gene encoding the histo-blood group B enzyme: rats have more than one Abo gene (2003), Glycobiology, 13, 919-928.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
monomorphic B-type gene Abo2, DNA and amino acid sequence determination and analysis, located on chromosome 3q11-q12, functional expression in CHO cells expressing the H precursor Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus Q8CFC4 B-type gene Abo2
-

Source Tissue

Source Tissue Comment Organism Textmining
cecum B-type enzyme expression in the surface epithelium Rattus norvegicus
-
kidney B-type enzyme expression Rattus norvegicus
-
large intestine B-type enzyme expression in the surface epithelium Rattus norvegicus
-
additional information no B-type enzyme expression in small intestine, striated muscle, heart, liver, lung, skin, uterus, testis, lymph node, or brain Rattus norvegicus
-
pancreas B-type enzyme expression Rattus norvegicus
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stomach B-type enzyme expression Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UDP-D-galactose + 2'-fucosyllactose
-
Rattus norvegicus UDP + D-galactosyl-(1-3)-2'-fucosyllactose
-
?
UDP-D-galactose + H type 3-Sp-biotin preferred substrates Rattus norvegicus UDP + ?
-
?
UDP-N-acetyl-D-galactosamine + 2'-fucosyllactose low A-type activity Rattus norvegicus UDP + N-acetyl-alpha-D-galactosaminyl-(1->3)-[alpha-L-fucosyl-(1->2)]-beta-D-galactosyl-(1->4)-beta-D-glucose
-
?
UDP-N-acetyl-D-galactosamine + H type 3-Sp-biotin low A-type activity Rattus norvegicus UDP + ?
-
?

Synonyms

Synonyms Comment Organism
histo-blood group B enzyme
-
Rattus norvegicus