Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.4.1.344 extracted from

  • Sun, J.; Thurin, J.; Cooper, H.S.; Wang, P.; Mackiewicz, M.; Steplewski, Z.; Blaszczyk-Thurin, M.
    Elevated expression of H type GDP-L-fucose:beta-D-galactoside alpha-2-L-fucosyltransferase is associated with human colon adenocarcinoma progression (1995), Proc. Natl. Acad. Sci. USA, 92, 5724-5728.
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
medicine transcript level for beta-D-galactoside alpha-2-L-fucosyltransferase is 40- and 340fold increased in all adenocarcinomas and tumor cell lines, respectively, compared to normal colon mucosa where a low level of mRNA transcript is detected. A variable increase in mRNA transcript levels is observed in 50% of adenomatous polyps. There are no tumor-associated allelic variations found within the H beta-D-galactoside alpha-2-Lfucosyltransferase cDNA Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining