Cloned (Comment) | Organism |
---|---|
transfection of Chinese hamster ovary cells | Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.024 | - |
GDP-beta-L-fucose | pH 7.2, 37°C | Rattus norvegicus | |
0.068 | - |
GDP-beta-L-fucose | pH 7.2, 37°C | Rattus norvegicus | |
5.2 | - |
beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosamine | pH 7.2, 37°C | Rattus norvegicus | |
20 | - |
beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosamine | pH 7.2, 37°C | Rattus norvegicus | |
25 | - |
phenyl beta-D-galactopyranoside | pH 7.2, 37°C | Rattus norvegicus | |
33 | - |
phenyl beta-D-galactopyranoside | pH 7.2, 37°C | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
GDP-beta-L-fucose + beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosamine | Rattus norvegicus | residues of H type 3 epitopes, reaction of EC 2.4.1.69 | GDP + alpha-L-fucosyl-(1->2)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosamine | - |
? | |
GDP-beta-L-fucose + beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosamine | Rattus norvegicus | residues of H type 1 epitopes, reaction of EC 2.4.1.69 | GDP + alpha-L-fucosyl-(1->2)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosamine | - |
? | |
GDP-beta-L-fucose + beta-D-galactosyl-(1->4)-N-acetyl-beta-D-galactosamine | Rattus norvegicus | residues of H type 3 epitopes, reaction of EC 2.4.1.69 | GDP + alpha-L-fucosyl-(1->2)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-galactosamine | - |
? | |
GDP-beta-L-fucose + beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosamine | Rattus norvegicus | residues of H type 2 epitopes | GDP + alpha-L-fucosyl-(1->2)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosamine | - |
? | |
GDP-beta-L-fucose + phenyl beta-D-galactopyranoside | Rattus norvegicus | - |
GDP + phenyl alpha-L-fucosyl-(1->2)-beta-D-galactopyranoside | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | Q10980 | - |
- |
Rattus norvegicus | Q10984 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
intestine | small and large intestine | Rattus norvegicus | - |
intestine | small and large intestines | Rattus norvegicus | - |
additional information | no cDNA detected in urinary bladder, the testis, the seminal vesicle, the ovary, the uterus, the spleen, the brain or muscle | Rattus norvegicus | - |
olfactory bulb | - |
Rattus norvegicus | - |
salivary gland | - |
Rattus norvegicus | - |
skin | - |
Rattus norvegicus | - |
stomach | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
GDP-beta-L-fucose + beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosamine | residues of H type 3 epitopes, reaction of EC 2.4.1.69 | Rattus norvegicus | GDP + alpha-L-fucosyl-(1->2)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosamine | - |
? | |
GDP-beta-L-fucose + beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosamine | residues of H type 1 epitopes, reaction of EC 2.4.1.69 | Rattus norvegicus | GDP + alpha-L-fucosyl-(1->2)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosamine | - |
? | |
GDP-beta-L-fucose + beta-D-galactosyl-(1->4)-N-acetyl-beta-D-galactosamine | residues of H type 3 epitopes, reaction of EC 2.4.1.69 | Rattus norvegicus | GDP + alpha-L-fucosyl-(1->2)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-galactosamine | - |
? | |
GDP-beta-L-fucose + beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosamine | residues of H type 2 epitopes | Rattus norvegicus | GDP + alpha-L-fucosyl-(1->2)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosamine | - |
? | |
GDP-beta-L-fucose + phenyl beta-D-galactopyranoside | - |
Rattus norvegicus | GDP + phenyl alpha-L-fucosyl-(1->2)-beta-D-galactopyranoside | - |
? |
Synonyms | Comment | Organism |
---|---|---|
FTA | - |
Rattus norvegicus |
Ftb | - |
Rattus norvegicus |
FUT1 | - |
Rattus norvegicus |
FUT2 | - |
Rattus norvegicus |
galactoside 2-alpha-L-fucosyltransferase 1 | - |
Rattus norvegicus |
galactoside 2-alpha-L-fucosyltransferase 2 | - |
Rattus norvegicus |
General Information | Comment | Organism |
---|---|---|
physiological function | isoform Fta allows synthesis of H type 2 and H type 3 histo-blood group antigen epitopes at the cell surface. In Chinese hamster ovary cells transfected by FTA, FTA is able to synthesize H type 2 epitopes on a large set of glycoproteins | Rattus norvegicus |