Literature summary for 2.4.1.317 extracted from

Wilson, V.T.; Cundliffe, E.
Characterization and targeted disruption of a glycosyltransferase gene in the tylosin producer, Streptomyces fradiae (1998), Gene, 214, 95-100.

Search for more literature for 2.4.1.317

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
46635	-	x * 46635, calculated from sequence	Streptomyces fradiae

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
5-O-beta-D-mycaminosyltylonolide + dTDP-6-deoxy-alpha-D-allose	Streptomyces fradiae	the enzyme participates in the biosynthetic pathway of the macrolide antibiotic tylosin	dTDP + demethyllactenocin	demethyllactenocin i.e. [(2R,3R,4E,6E,9R,11R,12S,13S,14R)-12-[[3,6-dideoxy-3-(dimethylamino)-D-glucopyranosyl]oxy]-2-ethyl-14-hydroxy-5,9,13-trimethyl-8,16-dioxo-11-(2-oxoethyl)oxacyclohexadeca-4,6-dien-3-yl]methyl 6-deoxy-beta-D-allopyranoside	?
5-O-beta-D-mycaminosyltylonolide + dTDP-6-deoxy-alpha-D-allose	Streptomyces fradiae T59235	the enzyme participates in the biosynthetic pathway of the macrolide antibiotic tylosin	dTDP + demethyllactenocin	demethyllactenocin i.e. [(2R,3R,4E,6E,9R,11R,12S,13S,14R)-12-[[3,6-dideoxy-3-(dimethylamino)-D-glucopyranosyl]oxy]-2-ethyl-14-hydroxy-5,9,13-trimethyl-8,16-dioxo-11-(2-oxoethyl)oxacyclohexadeca-4,6-dien-3-yl]methyl 6-deoxy-beta-D-allopyranoside	?

Organism

Organism	UniProt	Comment	Textmining
Streptomyces fradiae	O70023	-	-
Streptomyces fradiae T59235	O70023	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
5-O-beta-D-mycaminosyltylonolide + dTDP-6-deoxy-alpha-D-allose	-	Streptomyces fradiae	dTDP + demethyllactenocin	demethyllactenocin i.e. [(2R,3R,4E,6E,9R,11R,12S,13S,14R)-12-[[3,6-dideoxy-3-(dimethylamino)-D-glucopyranosyl]oxy]-2-ethyl-14-hydroxy-5,9,13-trimethyl-8,16-dioxo-11-(2-oxoethyl)oxacyclohexadeca-4,6-dien-3-yl]methyl 6-deoxy-beta-D-allopyranoside	?
5-O-beta-D-mycaminosyltylonolide + dTDP-6-deoxy-alpha-D-allose	the enzyme participates in the biosynthetic pathway of the macrolide antibiotic tylosin	Streptomyces fradiae	dTDP + demethyllactenocin	demethyllactenocin i.e. [(2R,3R,4E,6E,9R,11R,12S,13S,14R)-12-[[3,6-dideoxy-3-(dimethylamino)-D-glucopyranosyl]oxy]-2-ethyl-14-hydroxy-5,9,13-trimethyl-8,16-dioxo-11-(2-oxoethyl)oxacyclohexadeca-4,6-dien-3-yl]methyl 6-deoxy-beta-D-allopyranoside	?
5-O-beta-D-mycaminosyltylonolide + dTDP-6-deoxy-alpha-D-allose	-	Streptomyces fradiae T59235	dTDP + demethyllactenocin	demethyllactenocin i.e. [(2R,3R,4E,6E,9R,11R,12S,13S,14R)-12-[[3,6-dideoxy-3-(dimethylamino)-D-glucopyranosyl]oxy]-2-ethyl-14-hydroxy-5,9,13-trimethyl-8,16-dioxo-11-(2-oxoethyl)oxacyclohexadeca-4,6-dien-3-yl]methyl 6-deoxy-beta-D-allopyranoside	?
5-O-beta-D-mycaminosyltylonolide + dTDP-6-deoxy-alpha-D-allose	the enzyme participates in the biosynthetic pathway of the macrolide antibiotic tylosin	Streptomyces fradiae T59235	dTDP + demethyllactenocin	demethyllactenocin i.e. [(2R,3R,4E,6E,9R,11R,12S,13S,14R)-12-[[3,6-dideoxy-3-(dimethylamino)-D-glucopyranosyl]oxy]-2-ethyl-14-hydroxy-5,9,13-trimethyl-8,16-dioxo-11-(2-oxoethyl)oxacyclohexadeca-4,6-dien-3-yl]methyl 6-deoxy-beta-D-allopyranoside	?

Subunits

Subunits	Comment	Organism
?	x * 46635, calculated from sequence	Streptomyces fradiae

Synonyms

Synonyms	Comment	Organism
tylN	-	Streptomyces fradiae

General Information

General Information	Comment	Organism
physiological function	the enzyme participates in the biosynthetic pathway of the macrolide antibiotic tylosin	Streptomyces fradiae

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Release 2023.1 (January 2023)