Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Tequatrovirus T4 | the AGT with GT-B glycosyltransferase fold is responsible for DNA base flipping and substrate recognition, mechanism, overview | ? | - |
? | |
UDP-D-glucose + 5-hydroxymethyl cytosine | Tequatrovirus T4 | 5-hydroxymethyl cytosine residues of duplex DNA | UDP + 5-hydroxymethyl cytosine beta-D-glucoside | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Tequatrovirus T4 | - |
from Escherichia coli | - |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
UDP-alpha-D-glucose + 5-hydroxymethylcytosine containing DNA = UDP + beta-D-glucosyl-5-hydroxymethylcytosine containing DNA | catalytic mechanism, substrate binding structures, overview | Tequatrovirus T4 |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | the AGT with GT-B glycosyltransferase fold is responsible for DNA base flipping and substrate recognition, mechanism, overview | Tequatrovirus T4 | ? | - |
? | |
additional information | the alpha-linkage forming enzyme AGT is also able to adopt the fold of a GT-B glycosyltransferase keeping the sugar donor binding mechanism typical for GT-B glycosyltransferases, but showing a unique sugar acceptor binding mode, both substrates are bound to the C-terminal domain, detailed substrate binding structures, catalytic mechanism of both enzyme types, overview | Tequatrovirus T4 | ? | - |
? | |
UDP-D-glucose + 5-hydroxymethyl cytosine | 5-hydroxymethyl cytosine residues of duplex DNA | Tequatrovirus T4 | UDP + 5-hydroxymethyl cytosine beta-D-glucoside | - |
? |
Subunits | Comment | Organism |
---|---|---|
More | structural analysis of domain folding, substrate binding, catalytic mechanism, and base flipping mechanism, overview | Tequatrovirus T4 |
Synonyms | Comment | Organism |
---|---|---|
BGT | - |
Tequatrovirus T4 |
GT-B glycosyltransferase | - |
Tequatrovirus T4 |
More | the enzyme belongs to the GT-B glycosyltransferase family | Tequatrovirus T4 |