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Literature summary for 2.4.1.265 extracted from

  • Rehman, Z.U.; Wang, Y.; Moradali, M.F.; Hay, I.D.; Rehm, B.H.
    Insights into the assembly of the alginate biosynthesis machinery in Pseudomonas aeruginosa (2013), Appl. Environ. Microbiol., 79, 3264-3272.
    View publication on PubMedView publication on EuropePMC
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Organism

Organism UniProt Comment Textmining
Pseudomonas aeruginosa
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-
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Synonyms

Synonyms Comment Organism
ALG8
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 Pseudomonas aeruginosa

General Information

General Information Comment Organism
physiological function deletion of algK, a protein essential for alginate secretion, in an alginate-overproducing strain, PDO300, interferes with the polymerization of alginate, suggesting that in the absence of AlgK, the polymerase and copolymerase subunits, Alg8 and Alg44, are destabilized. Deletion of Alg8 resulted in the absence of AlgK, AlgX, and Alg44 from the envelope fraction and leads to a complete loss of production of alginate Pseudomonas aeruginosa