BRENDA - Enzyme Database show
show all sequences of 2.4.1.255

Dynamic O-GlcNAc modification of nucleocytoplasmic proteins in response to stress: A survival response of mammalian cells

Zachara, N.E.; O'Donnell, N.; Cheung, W.D.; Mercer, J.J.; Marth, J.D.; Hart, G.W.; J. Biol. Chem. 279, 30133-30142 (2004)

Data extracted from this reference:

Activating Compound
Activating Compound
Commentary
Organism
Structure
CoCl2
stress treatment induces higher levels of OGT protein expression
Chlorocebus aethiops
ethanol
stress treatment induces higher levels of OGT protein expression
Chlorocebus aethiops
H2O2
stress treatment induces higher levels of OGT protein expression
Chlorocebus aethiops
NaCl
stress treatment induces higher levels of OGT protein expression
Chlorocebus aethiops
sodium arsenite
stress treatment induces higher levels of OGT protein expression
Chlorocebus aethiops
UVB light
stress treatment induces higher levels of OGT protein expression
Chlorocebus aethiops
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Chlorocebus aethiops
-
-
-
Source Tissue
Source Tissue
Commentary
Organism
Textmining
COS-7 cell
-
Chlorocebus aethiops
-
Temperature Range [°C]
Temperature Minimum [°C]
Temperature Maximum [°C]
Commentary
Organism
additional information
-
stress treatment, different temperatures are representative of different basal levels of thermotolerance
Chlorocebus aethiops
Temperature Stability [°C]
Temperature Stability Minimum [°C]
Temperature Stability Maximum [°C]
Commentary
Organism
additional information
-
stress treatment, different temperatures are representative of different basal levels of thermotolerance
Chlorocebus aethiops
Activating Compound (protein specific)
Activating Compound
Commentary
Organism
Structure
CoCl2
stress treatment induces higher levels of OGT protein expression
Chlorocebus aethiops
ethanol
stress treatment induces higher levels of OGT protein expression
Chlorocebus aethiops
H2O2
stress treatment induces higher levels of OGT protein expression
Chlorocebus aethiops
NaCl
stress treatment induces higher levels of OGT protein expression
Chlorocebus aethiops
sodium arsenite
stress treatment induces higher levels of OGT protein expression
Chlorocebus aethiops
UVB light
stress treatment induces higher levels of OGT protein expression
Chlorocebus aethiops
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
COS-7 cell
-
Chlorocebus aethiops
-
Temperature Range [°C] (protein specific)
Temperature Minimum [°C]
Temperature Maximum [°C]
Commentary
Organism
additional information
-
stress treatment, different temperatures are representative of different basal levels of thermotolerance
Chlorocebus aethiops
Temperature Stability [°C] (protein specific)
Temperature Stability Minimum [°C]
Temperature Stability Maximum [°C]
Commentary
Organism
additional information
-
stress treatment, different temperatures are representative of different basal levels of thermotolerance
Chlorocebus aethiops
Other publictions for EC 2.4.1.255
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
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197
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1
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1
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Enhanced transfer of a photocr ...
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290
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2015
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4
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4
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2015
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736868
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The active site of O-GlcNAc tr ...
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Nat. Struct. Mol. Biol.
22
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2015
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5
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2015
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1
4
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1
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1
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735633
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457
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735732
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736080
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FASEB J.
28
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2014
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1
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736452
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289
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2014
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2
737109
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8
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2
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737111
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8
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2013
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721254
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302
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2012
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721502
Sakaidani
O-linked-N-acetylglucosamine m ...
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Biochem. Biophys. Res. Commun.
419
14-19
2012
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721991
Ruan
O-GlcNAc transferase/host cell ...
Homo sapiens
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16
226-237
2012
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2
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722455
Tvaroska
Substrate-assisted catalytic m ...
Homo sapiens
J. Am. Chem. Soc.
134
15563-15571
2012
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722752
Shen
Insights into O-linked N-acety ...
Homo sapiens
J. Biol. Chem.
287
15395-15408
2012
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2
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5
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1
1
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4
4
722774
Gawlowski
Modulation of dynamin-related ...
Rattus norvegicus
J. Biol. Chem.
287
30024-30034
2012
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722803
Iwashita
Genome-wide repression of NF-k ...
Homo sapiens
J. Biol. Chem.
287
9887-9900
2012
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1
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1
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2
2
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723250
Jiang
A neutral diphosphate mimic cr ...
Homo sapiens
Nat. Chem. Biol.
8
72-77
2012
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1
1
8
-
6
-
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2
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1
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1
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8
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6
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723251
Lazarus
Structural snapshots of the re ...
Homo sapiens
Nat. Chem. Biol.
8
966-968
2012
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1
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1
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1
1
1
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1
1
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6
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6
9
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1
2
1
3
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1
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1
1
1
1
1
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1
1
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