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Literature summary for 2.4.1.245 extracted from

  • Kim, H.; Chang, Y.; Ryu, S.; Moon, S.; Lee, S.
    Enzymatic synthesis of a galactose-containing trehalose analogue disaccharide by Pyrococcus horikoshii trehalose-synthesizing glycosyltransferase Inhibitory effects on several disaccharidase activities (2007), J. Mol. Catal. B, 49, 98-103 .
No PubMed abstract available
Search for more literature for 2.4.1.245

Application

Application Comment Organism
synthesis synthesis of the trehalase analogue alpha-D-Glc-(1->1)-alpha-D-Glc, that might be effective at inhibiting intestinal brush-order disaccharidases Pyrococcus horikoshii

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.6
-
 D-glucose pH 7.0, 37°C Pyrococcus horikoshii
12.7
-
 D-galactose pH 7.0, 37°C Pyrococcus horikoshii

Organism

Organism UniProt Comment Textmining
Pyrococcus horikoshii O58762
-
-
Pyrococcus horikoshii OT-3 O58762
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UDP-alpha-D-glucose + D-galactose
-
 Pyrococcus horikoshii alpha-D-Glc-(1->1)-alpha-D-Glc + UDP
-
 ?
UDP-alpha-D-glucose + D-galactose
-
 Pyrococcus horikoshii OT-3 alpha-D-Glc-(1->1)-alpha-D-Glc + UDP
-
 ?
UDP-alpha-D-glucose + D-glucose
-
 Pyrococcus horikoshii alpha,alpha-trehalose + UDP
-
 ?
UDP-alpha-D-glucose + D-glucose
-
 Pyrococcus horikoshii OT-3 alpha,alpha-trehalose + UDP
-
 ?

Synonyms

Synonyms Comment Organism
PH1035
-
 Pyrococcus horikoshii

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Pyrococcus horikoshii

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7
-
 assay at Pyrococcus horikoshii