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Literature summary for 2.4.1.229 extracted from
- Cytoplasmic glycosylation of protein-hydroxyproline and its relationship to other glycosylation pathways (2004), Biochim. Biophys. Acta, 1673, 29-44.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| DTT | absolutely dependent on | Dictyostelium discoideum |  |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytoplasm | - |
Dictyostelium discoideum | 5737 | - |
| cytoplasm | - |
Phytophthora sojae | 5737 | - |
| cytoplasm | - |
Thalassiosira pseudonana | 5737 | - |
| cytoplasm | - |
Chlamydomonas reinhardtii | 5737 | - |
| cytoplasm | - |
Toxoplasma gondii | 5737 | - |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mn2+ | absolutely dependent on | Dictyostelium discoideum | |
| additional information | enzyme prefers low salt conditions, absolutely dependent on divalent cations | Chlamydomonas reinhardtii | |
| additional information | enzyme prefers low salt conditions | Dictyostelium discoideum | |
| additional information | enzyme prefers low salt conditions, absolutely dependent on divalent cations | Phytophthora sojae | |
| additional information | enzyme prefers low salt conditions, absolutely dependent on divalent cations | Thalassiosira pseudonana | |
| additional information | enzyme prefers low salt conditions, absolutely dependent on divalent cations | Toxoplasma gondii |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| UDP-N-acetylglucosamine + polypeptide-hydroxyamino acid | Phytophthora sojae | - |
UDP + polypeptide-O-(alpha-N-acetyl-D-glucosaminyl)hydroxyamino acid | - |
? | |
| UDP-N-acetylglucosamine + polypeptide-hydroxyamino acid | Thalassiosira pseudonana | - |
UDP + polypeptide-O-(alpha-N-acetyl-D-glucosaminyl)hydroxyamino acid | - |
? | |
| UDP-N-acetylglucosamine + polypeptide-hydroxyamino acid | Chlamydomonas reinhardtii | - |
UDP + polypeptide-O-(alpha-N-acetyl-D-glucosaminyl)hydroxyamino acid | - |
? | |
| UDP-N-acetylglucosamine + polypeptide-hydroxyamino acid | Toxoplasma gondii | - |
UDP + polypeptide-O-(alpha-N-acetyl-D-glucosaminyl)hydroxyamino acid | - |
? | |
| UDP-N-acetylglucosamine + [Skp1-protein]-hydroxyproline | Dictyostelium discoideum | enzyme is involved in O-glycosylation of Skp1-protein and mucin formation | UDP + [Skp1-protein]-O-(alpha-N-acetyl-D-glucosaminyl)hydroxyproline | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Chlamydomonas reinhardtii | - |
- |
- |
| Dictyostelium discoideum | Q8MZN0 | - |
- |
| Phytophthora sojae | - |
- |
- |
| Thalassiosira pseudonana | - |
- |
- |
| Toxoplasma gondii | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| UDP-N-acetylglucosamine + polypeptide-hydroxyamino acid | - |
Phytophthora sojae | UDP + polypeptide-O-(alpha-N-acetyl-D-glucosaminyl)hydroxyamino acid | - |
? | |
| UDP-N-acetylglucosamine + polypeptide-hydroxyamino acid | - |
Thalassiosira pseudonana | UDP + polypeptide-O-(alpha-N-acetyl-D-glucosaminyl)hydroxyamino acid | - |
? | |
| UDP-N-acetylglucosamine + polypeptide-hydroxyamino acid | - |
Chlamydomonas reinhardtii | UDP + polypeptide-O-(alpha-N-acetyl-D-glucosaminyl)hydroxyamino acid | - |
? | |
| UDP-N-acetylglucosamine + polypeptide-hydroxyamino acid | - |
Toxoplasma gondii | UDP + polypeptide-O-(alpha-N-acetyl-D-glucosaminyl)hydroxyamino acid | - |
? | |
| UDP-N-acetylglucosamine + [Skp1-protein]-hydroxyproline | enzyme is involved in O-glycosylation of Skp1-protein and mucin formation | Dictyostelium discoideum | UDP + [Skp1-protein]-O-(alpha-N-acetyl-D-glucosaminyl)hydroxyproline | - |
? | |
| UDP-N-acetylglucosamine + [Skp1-protein]-hydroxyproline | enzyme is highly specific for the Skp1-protein | Dictyostelium discoideum | UDP + [Skp1-protein]-O-(alpha-N-acetyl-D-glucosaminyl)hydroxyproline | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Dd-ppGnT1 | - |
Dictyostelium discoideum |
| GnT51 | - |
Dictyostelium discoideum |
| Skp1 alpha-GlcNAcT1 | - |
Dictyostelium discoideum |
| Skp1 alpha-GlcNAcT1-like enzyme | - |
Phytophthora sojae |
| Skp1 alpha-GlcNAcT1-like enzyme | - |
Thalassiosira pseudonana |
| Skp1 alpha-GlcNAcT1-like enzyme | - |
Chlamydomonas reinhardtii |
| Skp1 alpha-GlcNAcT1-like enzyme | - |
Toxoplasma gondii |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| additional information | - |
neutral pH-optimum | Dictyostelium discoideum |
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