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Literature summary for 2.4.1.229 extracted from

  • West, C.M.; van der Wel, H.; Gaucher, E.A.
    Complex glycosylation of Skp1 in Dictyostelium: implications for the modification of other eukaryotic cytoplasmic and nuclear proteins (2002), Glycobiology, 12, 17R-27R.
    View publication on PubMed
Search for more literature for 2.4.1.229

Activating Compound

Activating Compound Comment Organism Structure
additional information requires reducing condition Dictyostelium sp.

Cloned(Commentary)

Cloned (Comment) Organism
-
 Dictyostelium discoideum

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Dictyostelium sp. 5829
-
cytosol
-
 Dictyostelium discoideum 5829
-
additional information away from membranes Dictyostelium sp.
-
-

Metals/Ions

Metals/Ions Comment Organism Structure
additional information divalent cations required Dictyostelium sp.

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
51000
-
 1 * 51000, SDS-PAGE Dictyostelium sp.

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
UDP-N-acetylglucosamine + [Skp1-protein]-hydroxyproline Dictyostelium discoideum
-
 UDP + [Skp1-protein]-O-(N-acetyl-D-glucosaminyl)hydroxyproline
-
 ?
UDP-N-acetylglucosamine + [Skp1-protein]-hydroxyproline Dictyostelium sp. part of complex O-linked glycosylation, which is necessary for targeting of Skp-1-protein to the nucleus UDP + [Skp1-protein]-O-(N-acetyl-D-glucosaminyl)hydroxyproline
-
 ?

Organism

Organism UniProt Comment Textmining
Dictyostelium discoideum Q8T1C6 gene GnT51
-
Dictyostelium sp.
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Dictyostelium sp.

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information no activity with nonhydroxylated Skp-1-protein or -peptide Dictyostelium sp. ?
-
 ?
UDP-N-acetylglucosamine + hydroxyproline-peptide synthetic peptide substrate Dictyostelium sp. UDP + (N-acetyl-D-glucosaminyl)hydroxyproline peptide
-
 ?
UDP-N-acetylglucosamine + [Skp1-protein]-hydroxyproline
-
 Dictyostelium discoideum UDP + [Skp1-protein]-O-(N-acetyl-D-glucosaminyl)hydroxyproline
-
 ?
UDP-N-acetylglucosamine + [Skp1-protein]-hydroxyproline enzyme attaches the first sugar of pentasaccharide chain Dictyostelium discoideum UDP + [Skp1-protein]-O-(N-acetyl-D-glucosaminyl)hydroxyproline
-
 ?
UDP-N-acetylglucosamine + [Skp1-protein]-hydroxyproline hydroxyproline143 Dictyostelium sp. UDP + [Skp1-protein]-O-(N-acetyl-D-glucosaminyl)hydroxyproline
-
 ?
UDP-N-acetylglucosamine + [Skp1-protein]-hydroxyproline hydroxyproline143 Dictyostelium discoideum UDP + [Skp1-protein]-O-(N-acetyl-D-glucosaminyl)hydroxyproline
-
 ?
UDP-N-acetylglucosamine + [Skp1-protein]-hydroxyproline recombinant protein substrate, deficient in GlcNAc Dictyostelium sp. UDP + [Skp1-protein]-O-(N-acetyl-D-glucosaminyl)hydroxyproline
-
 ?
UDP-N-acetylglucosamine + [Skp1-protein]-hydroxyproline part of complex O-linked glycosylation, which is necessary for targeting of Skp-1-protein to the nucleus Dictyostelium sp. UDP + [Skp1-protein]-O-(N-acetyl-D-glucosaminyl)hydroxyproline
-
 ?

Subunits

Subunits Comment Organism
monomer 1 * 51000, SDS-PAGE Dictyostelium sp.

Synonyms

Synonyms Comment Organism
GnT51
-
 Dictyostelium sp.
GnT51
-
 Dictyostelium discoideum