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Literature summary for 2.4.1.225 extracted from

  • Sembajwe, L.; Katta, K.; Gronning, M.; Kusche-Gullberg, M.
    The exostosin family of glycosyltransferases MRNA expression profiles and heparan sulphate structure in human breast carcinoma cell lines (2018), Biosci. Rep., 38, 1-12 .
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Homo sapiens Q16394
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-
Homo sapiens Q93063
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-

Source Tissue

Source Tissue Comment Organism Textmining
breast cancer cell line
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Homo sapiens
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HCC-38 cell
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Homo sapiens
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MCF-10A cell
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Homo sapiens
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MDA-MB-231 cell
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Homo sapiens
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Synonyms

Synonyms Comment Organism
EXT1
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Homo sapiens
EXT2
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Homo sapiens

Expression

Organism Comment Expression
Homo sapiens EXT1 is significantly decreased in MCF7 cells compared with the non-tumorigenic MCF10A cells, while no significant difference is observed between the two triple-negative cell lines, MDA-MB-231 and HCC38, and the ER- and PR-positive MCF10A cells down
Homo sapiens the expression of EXT2 is reduced in all cancer cell lines down
Homo sapiens EXT2 is down-regulated in MDA-MB-231 and HCC38 epithelial breast carcinoma cell lines up