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Literature summary for 2.4.1.224 extracted from

  • Okolicsanyi, R.K.; Bluhm, J.; Miller, C.; Griffiths, L.R.; Haupt, L.M.
    An investigation of genetic polymorphisms in heparan sulfate proteoglycan core proteins and key modification enzymes in an Australian Caucasian multiple sclerosis population (2020), Hum. Genomics, 14, 18 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.4.1.224

Organism

Organism UniProt Comment Textmining
Homo sapiens Q16394
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Homo sapiens Q16394 Australian Caucasian multiple sclerosis population
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Synonyms

Synonyms Comment Organism
exostosin-1
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 Homo sapiens
EXT1
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 Homo sapiens

General Information

General Information Comment Organism
physiological function key enzyme contributing to the generation of heparan sulfate chains. EXT1, with tumour suppressor properties, is involved in the initiation and polymerisation of the growing heparan sulfate chain. The study may suggest that no association exists between EXT1 and multiple sclerosis Homo sapiens
physiological function key enzymes contributing to the generation of heparan sulfate chains. EXT1, with documented tumour suppressor properties, is involved in the initiation and polymerisation of the growing heparan sulfate chain Homo sapiens