BRENDA - Enzyme Database
show all sequences of 2.4.1.223

Distinct and collaborative roles of Drosophila EXT family proteins in morphopgen signalling and gradient formation

Han, C.; Belenkaya, T.Y.; Khodoun, M.; Tauchi, M.; Lin, X.; Lin, X.; Development 131, 1563-1575 (2005)

Data extracted from this reference:

Engineering
Amino acid exchange
Commentary
Organism
additional information
enzyme null mutant, defects in Hedgehog, Wingless and Decapentaplegic signalling
Drosophila melanogaster
Localization
Localization
Commentary
Organism
GeneOntology No.
Textmining
endoplasmic reticulum
-
Drosophila melanogaster
5783
-
Golgi apparatus
-
Drosophila melanogaster
5794
-
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Drosophila melanogaster
-
enzyme botv, homologue of mammalian EXTL3
-
Engineering (protein specific)
Amino acid exchange
Commentary
Organism
additional information
enzyme null mutant, defects in Hedgehog, Wingless and Decapentaplegic signalling
Drosophila melanogaster
Localization (protein specific)
Localization
Commentary
Organism
GeneOntology No.
Textmining
endoplasmic reticulum
-
Drosophila melanogaster
5783
-
Golgi apparatus
-
Drosophila melanogaster
5794
-
Other publictions for EC 2.4.1.223
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
686299
Herr
Regulation of TGF-beta signall ...
Xenopus laevis
Development
135
1813-1822
2008
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1
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1
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4
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4
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2
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4
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661562
Han
Distinct and collaborative rol ...
Drosophila melanogaster
Development
131
1563-1575
2005
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662163
Kim
In vitro heparan sulfate polym ...
Homo sapiens
J. Biol. Chem.
278
41618-41623
2003
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1
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488961
Kim
Demonstration of a novel gene ...
Drosophila melanogaster
J. Biol. Chem.
277
13659-13665
2002
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1
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1
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488951
Kitagawa
rib-2, a Caenorhabditis elegan ...
Caenorhabditis elegans
J. Biol. Chem.
276
4834-4838
2001
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1
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488960
Kim
Human tumor suppressor EXT gen ...
Homo sapiens
Proc. Natl. Acad. Sci. USA
98
7176-7181
2001
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1
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1
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1
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662102
Kitagawa
The tumor suppressor EXT-like ...
Homo sapiens
J. Biol. Chem.
274
13933-13937
1999
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