Literature summary for 2.4.1.222 extracted from

Arboleda-Velasquez, J.F.; Rampal, R.; Fung, E.; Darland, D.C.; Liu, M.; Martinez, M.C.; Donahue, C.P.; Navarro-Gonzalez, M.F.; Libby, P.; DAmore, P.A.; Aikawa, M.; Haltiwanger, R.S.; Kosik, K.S.
CADASIL mutations impair Notch3 glycosylation by Fringe (2005), Hum. Mol. Genet., 14, 1631-1639.

Search for more literature for 2.4.1.222

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
additional information	Mus musculus	Fringe elongates O-fucose residues on EGF-like repeat 4 and 5 of Notch3. Fringe plays a role in CADASIL pathophysiology	?	-	?

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	Fringe elongates O-fucose residues on EGF-like repeat 4 and 5 of Notch3. Fringe plays a role in CADASIL pathophysiology	Mus musculus	?	-	?

Synonyms

Synonyms	Comment	Organism
Lunatic Fringe	-	Mus musculus

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)