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Literature summary for 2.4.1.22 extracted from

  • Landers, E.; Burkin, H.; Bleck, G.; Howell-Skalla, L.; Miller, D.
    Porcine beta1,4-galactosyltransferase-I sequence and expression (2009), Reprod. Domest. Anim., 44, 228-234.
    View publication on PubMed
Search for more literature for 2.4.1.22

Cloned(Commentary)

Cloned (Comment) Organism
gene B4GALT1, DNA and amino acid sequence determination and analysis, RT-PCR expression analysis, sequence comparison Sus scrofa

Localization

Localization Comment Organism GeneOntology No. Textmining
Golgi apparatus trans-Golgi complex, beta1,4-galactosyltransferase-I Sus scrofa 5794
-
membrane B4GALT1 is a type II transmembrane enzyme Sus scrofa 16020
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
UDP-galactose + D-glucose Sus scrofa
-
 UDP + lactose
-
 ?

Organism

Organism UniProt Comment Textmining
Sus scrofa
-
 the beta1,4-galactosyltransferase-I component is encoded by gene B4GALT1
-

Posttranslational Modification

Posttranslational Modification Comment Organism
glycoprotein N-glycosylation of B4GALT1 Sus scrofa

Source Tissue

Source Tissue Comment Organism Textmining
mammary gland alpha-lactalbumin, a mammary-specific protein Sus scrofa
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information beta1,4-galactosyltransferase-I forms a complex with alpha-lactalbumin to give lactose synthase Sus scrofa ?
-
 ?
UDP-galactose + D-glucose
-
 Sus scrofa UDP + lactose
-
 ?
UDP-galactose + D-glucose formation of a beta(1-4)linkage Sus scrofa UDP + lactose
-
 ?