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Literature summary for 2.4.1.22 extracted from

  • Reich, C.M.; Arnould, J.P.
    Evolution of Pinnipedia lactation strategies: a potential role for alpha-lactalbumin? (2007), Biol. Lett., 3, 546-549.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.4.1.22

Cloned(Commentary)

Cloned (Comment) Organism
DNA and amino acid sequence determination and analysis of alpha-lactalbumin component of the lactose synthase complex, aberrant splicing is responsible for the two cDNA variants isolated from mammary tissue, with the longer variant maintaining the third intron and the shorter variant, phylogenetic analysis Arctocephalus tropicalis
DNA and amino acid sequence determination and analysis of alpha-lactalbumin component of the lactose synthase complex, aberrant splicing is responsible for the two cDNA variants isolated from mammary tissue, with the longer variant maintaining the third intron and the shorter variant, phylogenetic analysis Arctocephalus pusillus pusillus
DNA and amino acid sequence determination and analysis of alpha-lactalbumin component of the lactose synthase complex, phylogenetic analysis Odobenus rosmarus rosmarus
DNA and amino acid sequence determination and analysis of alpha-lactalbumin component of the lactose synthase complex, phylogenetic analysis Callorhinus ursinus
DNA and amino acid sequence determination and analysis of alpha-lactalbumin component of the lactose synthase complex, phylogenetic analysis Zalophus californianus
DNA and amino acid sequence determination and analysis of alpha-lactalbumin component of the lactose synthase complex, phylogenetic analysis Neophoca cinerea
DNA and amino acid sequence determination and analysis of alpha-lactalbumin component of the lactose synthase complex, phylogenetic analysis Leptonychotes weddellii
DNA and amino acid sequence determination and analysis of alpha-lactalbumin component of the lactose synthase complex, phylogenetic analysis Pusa hispida

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
UDP-galactose + D-glucose Odobenus rosmarus rosmarus
-
 UDP + lactose
-
 ?
UDP-galactose + D-glucose Arctocephalus tropicalis
-
 UDP + lactose
-
 ?
UDP-galactose + D-glucose Arctocephalus pusillus pusillus
-
 UDP + lactose
-
 ?
UDP-galactose + D-glucose Callorhinus ursinus
-
 UDP + lactose
-
 ?
UDP-galactose + D-glucose Zalophus californianus
-
 UDP + lactose
-
 ?
UDP-galactose + D-glucose Neophoca cinerea
-
 UDP + lactose
-
 ?
UDP-galactose + D-glucose Leptonychotes weddellii
-
 UDP + lactose
-
 ?
UDP-galactose + D-glucose Pusa hispida
-
 UDP + lactose
-
 ?

Organism

Organism UniProt Comment Textmining
Arctocephalus pusillus pusillus A7TWS3 short isoform of alpha-lactalbumin; South African fur seal
-
Arctocephalus pusillus pusillus A7TWS4 long isoform of alpha-lactalbumin; South African fur seal
-
Arctocephalus tropicalis A7TWS1 short isoform of alpha-lactalbumin; subantarctic fur seal
-
Arctocephalus tropicalis A7TWS2 long isoform of alpha-lactalbumin; subantarctic fur seal
-
Callorhinus ursinus A7TWS5 alpha-lactalbumin fragment; Northern fur seal
-
Leptonychotes weddellii A7TWS8 alpha-lactalbumin; Weddell seal
-
Neophoca cinerea A7TWS7 alpha-lactalbumin fragment; Australian sea lion
-
Odobenus rosmarus rosmarus A7TWT0 alpha-lactalbumin; atlantic walrus
-
Pusa hispida B7SHL6 alpha-lactalbumin fragment; i.e. Pusa hispida, ringed seal
-
Zalophus californianus A7TWS6 alpha-lactalbumin; California sealion
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Odobenus rosmarus rosmarus
-
liver
-
 Arctocephalus tropicalis
-
liver
-
 Arctocephalus pusillus pusillus
-
liver
-
 Callorhinus ursinus
-
liver
-
 Zalophus californianus
-
liver
-
 Neophoca cinerea
-
liver
-
 Leptonychotes weddellii
-
liver
-
 Pusa hispida
-
mammary gland
-
 Odobenus rosmarus rosmarus
-
mammary gland
-
 Arctocephalus tropicalis
-
mammary gland
-
 Arctocephalus pusillus pusillus
-
mammary gland
-
 Callorhinus ursinus
-
mammary gland
-
 Zalophus californianus
-
mammary gland
-
 Neophoca cinerea
-
mammary gland
-
 Leptonychotes weddellii
-
mammary gland
-
 Pusa hispida
-
milk
-
 Odobenus rosmarus rosmarus
-
milk
-
 Arctocephalus tropicalis
-
milk
-
 Arctocephalus pusillus pusillus
-
milk
-
 Callorhinus ursinus
-
milk
-
 Zalophus californianus
-
milk
-
 Neophoca cinerea
-
milk
-
 Leptonychotes weddellii
-
milk
-
 Pusa hispida
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UDP-galactose + D-glucose
-
 Odobenus rosmarus rosmarus UDP + lactose
-
 ?
UDP-galactose + D-glucose
-
 Arctocephalus tropicalis UDP + lactose
-
 ?
UDP-galactose + D-glucose
-
 Arctocephalus pusillus pusillus UDP + lactose
-
 ?
UDP-galactose + D-glucose
-
 Callorhinus ursinus UDP + lactose
-
 ?
UDP-galactose + D-glucose
-
 Zalophus californianus UDP + lactose
-
 ?
UDP-galactose + D-glucose
-
 Neophoca cinerea UDP + lactose
-
 ?
UDP-galactose + D-glucose
-
 Leptonychotes weddellii UDP + lactose
-
 ?
UDP-galactose + D-glucose
-
 Pusa hispida UDP + lactose
-
 ?
UDP-galactose + D-glucose residues necessary for lactose synthesis activity are Phe31, His32, Leu110, Gln117 and Trp118 of alpha-lactalbumin Odobenus rosmarus rosmarus UDP + lactose
-
 ?
UDP-galactose + D-glucose residues necessary for lactose synthesis activity are Phe31, His32, Leu110, Gln117 and Trp118 of alpha-lactalbumin Arctocephalus tropicalis UDP + lactose
-
 ?
UDP-galactose + D-glucose residues necessary for lactose synthesis activity are Phe31, His32, Leu110, Gln117 and Trp118 of alpha-lactalbumin Arctocephalus pusillus pusillus UDP + lactose
-
 ?
UDP-galactose + D-glucose residues necessary for lactose synthesis activity are Phe31, His32, Leu110, Gln117 and Trp118 of alpha-lactalbumin Callorhinus ursinus UDP + lactose
-
 ?
UDP-galactose + D-glucose residues necessary for lactose synthesis activity are Phe31, His32, Leu110, Gln117 and Trp118 of alpha-lactalbumin Zalophus californianus UDP + lactose
-
 ?
UDP-galactose + D-glucose residues necessary for lactose synthesis activity are Phe31, His32, Leu110, Gln117 and Trp118 of alpha-lactalbumin Neophoca cinerea UDP + lactose
-
 ?
UDP-galactose + D-glucose residues necessary for lactose synthesis activity are Phe31, His32, Leu110, Gln117 and Trp118 of alpha-lactalbumin Leptonychotes weddellii UDP + lactose
-
 ?
UDP-galactose + D-glucose residues necessary for lactose synthesis activity are Phe31, His32, Leu110, Gln117 and Trp118 of alpha-lactalbumin Pusa hispida UDP + lactose
-
 ?