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Literature summary for 2.4.1.218 extracted from

  • Huma, T.; Maryam, A.; Qamar, T.U.
    Molecular modeling and docking of wheat hydroquinone glucosyl transferase by using hydroquinone, phenyl phosphorodiamate and n-(n butyl) phosphorothiocic triamide as inhibitors (2014), Bioinformation, 10, 124-129.
    View publication on PubMedView publication on EuropePMC

Inhibitors

Inhibitors Comment Organism Structure
hydroquinone Glu274 is acting as an acidic backbone acceptor residue. Lys262, a basic amino acid from the active site of wheat Hydroquinone glucosyltransferase interacts with the hydroxyl group of hydroquinone and behaves as a side chain donor molecule. Asp264 is also observed as an interacting residue from the active site of hydroquinone glucosyltransferase. It binds to the hydroxyl group of hydroquinone inhibitor and donates hydrogen ion from its side chain group Triticum aestivum
additional information enzyme molecular docking of urease inhibitors hydroquinone, phenyl phosphorodiamate, and N-(n-butyl) phosphorothiocic triamide, three-dimensional structure analysis using homology modeling, and interactions analysis, overview Triticum aestivum
N-(n-butyl) phosphorothiocic triamide Glu274 is acting as an acidic backbone donor residue and interacts with the amino group of the inhibitor Triticum aestivum
phenyl phosphorodiamate Glu395 is directly interacting with amino group of the inhibitor Triticum aestivum

Metals/Ions

Metals/Ions Comment Organism Structure
Ni2+ required, metalloenzyme Triticum aestivum

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
UDP-glucose + hydroquinone Triticum aestivum
-
UDP + hydroquinone-O-beta-D-glucopyranoside
-
?

Organism

Organism UniProt Comment Textmining
Triticum aestivum D8LAL9
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UDP-glucose + hydroquinone
-
Triticum aestivum UDP + hydroquinone-O-beta-D-glucopyranoside
-
?

Synonyms

Synonyms Comment Organism
hydroquinone glucosyl transferase
-
Triticum aestivum