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Literature summary for 2.4.1.214 extracted from

  • Weninger, W.; Ulfman, L.H.; Cheng, G.; Souchkova, N.; Quackenbush, E.J.; Lowe, J.B.; von Andrian, U.H.
    Specialized contributions by alpha(1,3)-fucosyltransferase-IV and FucT-VII during leukocyte rolling in dermal microvessels (2000), Immunity, 12, 665-676.
    View publication on PubMed
Search for more literature for 2.4.1.214

Protein Variants

Protein Variants Comment Organism
additional information mice deficient in alpha(1,3)-fucosyltransferase-IV, i.e. FucT IV-/- mice, show a normal leukocyte rolling fraction, but increased rolling velocity, mice deficient in alpha(1,3)-fucosyltransferase-VII, i.e. FucT VII-/- mice, show a reduced leukocyte rolling fraction and increased rolling velocity Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Mus musculus FucT-IV E- and P-selectin ligand precursors to give mature E- and P-selectin ligands, 3-alpha-fucosylates FucT-VII 3-alpha-fucosylates P-selectin ligand precursors to give mature P-selectin ligands that are essential for control of frequency of and all interaction related to leukocyte rolling, overview, FucT-IV and FucT-VII show overlapping activities in the immunosurveillance of the skin ?
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 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
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Source Tissue

Source Tissue Comment Organism Textmining
leukocyte
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 Mus musculus
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skin
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 Mus musculus
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venule
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 Mus musculus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information FucT-IV E- and P-selectin ligand precursors to give mature E- and P-selectin ligands, 3-alpha-fucosylates FucT-VII 3-alpha-fucosylates P-selectin ligand precursors to give mature P-selectin ligands that are essential for control of frequency of and all interaction related to leukocyte rolling, overview, FucT-IV and FucT-VII show overlapping activities in the immunosurveillance of the skin Mus musculus ?
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 ?

Synonyms

Synonyms Comment Organism
alpha(1,3)-fucosyltransferase-IV
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 Mus musculus
alpha(1,3)-fucosyltransferase-VII
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 Mus musculus
FucT-IV
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 Mus musculus
FucT-VII
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 Mus musculus