Cloned (Comment) | Organism |
---|---|
expressed in a baculovirus-Sf9 cell system | Mus musculus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00318 | - |
17beta-estradiol | isoform Ugt1a1, at pH 7.4 and 37°C | Mus musculus | |
0.24 | - |
morphine | isoform Ugt2b36, at pH 7.4 and 37°C | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | Q3UEP4 | - |
- |
Mus musculus | Q63886 | - |
- |
Mus musculus | Q8K154 | - |
- |
Mus musculus | Q8VCN3 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Mus musculus | - |
liver | isoform Ugt2b36 is highly expressed in the liver | Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
17beta-estradiol + UDP-alpha-D-glucuronate | - |
Mus musculus | UDP + estradiol-3beta-D-glucuronoside | - |
? | |
4-methylumbelliferone + UDP-glucuronate | - |
Mus musculus | UDP + 4-methylumbelliferyl beta-D-glucuronide | - |
? | |
morphine + UDP-glucuronate | - |
Mus musculus | UDP + morphine beta-D-glucuronide | - |
? | |
morphine + UDP-glucuronate | Ugt2b36 is the predominant isoform involved in morphine glucuronidation | Mus musculus | UDP + morphine beta-D-glucuronide | - |
? | |
UDP-alpha-D-glucuronate + chloramphenicol | - |
Mus musculus | UDP + chloramphenicol beta-D-glucuronide | - |
? |
Synonyms | Comment | Organism |
---|---|---|
UDP-glucuronosyltransferase | - |
Mus musculus |
UGT1A1 | isoform | Mus musculus |
Ugt2b34 | isoform | Mus musculus |
Ugt2b36 | isoform | Mus musculus |
Ugt2b37 | isoform | Mus musculus |