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Literature summary for 2.4.1.17 extracted from

  • Pan, Y.; Xu, P.; Zeng, X.; Liu, X.; Shang, Q.
    Characterization of UDP-glucuronosyltransferases and the potential contribution to nicotine tolerance in Myzus persicae (2019), Int. J. Mol. Sci., 20, 3637 .
    View publication on PubMedView publication on EuropePMC

Inhibitors

Inhibitors Comment Organism Structure
5-Nitrouracil
-
Myzus persicae nicotianae
sulfinpyrazone
-
Myzus persicae nicotianae

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
UDP-alpha-D-glucuronate + acceptor Myzus persicae nicotianae
-
UDP + acceptor beta-D-glucuronoside
-
?

Organism

Organism UniProt Comment Textmining
Myzus persicae nicotianae
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UDP-alpha-D-glucuronate + acceptor
-
Myzus persicae nicotianae UDP + acceptor beta-D-glucuronoside
-
?

Synonyms

Synonyms Comment Organism
UDP-glucuronosyltransferase
-
Myzus persicae nicotianae
UGT330A3 isoform Myzus persicae nicotianae
UGT339A2 isoform Myzus persicae nicotianae
UGT341A6 isoform Myzus persicae nicotianae
UGT342B3 isoform Myzus persicae nicotianae
UGT343C3 isoform Myzus persicae nicotianae
UGT344D5 isoform Myzus persicae nicotianae
UGT344D8 isoform Myzus persicae nicotianae
UGT348A3 isoform Myzus persicae nicotianae
UGT349A3 isoform Myzus persicae nicotianae
UGT350A3 isoform Myzus persicae nicotianae

General Information

General Information Comment Organism
malfunction knockdown of isoforms UGT330A3, UGT344D5, UGT348A3, and UGT349A3 significantly increases Myzus persicae nicotianae sensitivity to nicotine Myzus persicae nicotianae
physiological function the enzyme is associated with nicotine tolerance and thus host adaptation in Myzus persicae nicotianae Myzus persicae nicotianae